Important Information About Adderall

Adderall is a psychostimulant, a drug of the phenethylamine group, used in some countries for the treatment of an attention deficit hyperactivity disorder and narcolepsy. Adderall consists of amphetamine salts: dextroamphetamine (75%) and levoamphetamine (25%). Adderall significantly increases the activity of dopamine and norepinephrine.

Important facts you should know about Adderall before taking it:

  • Adderall can be taken orally, rectally, sublingually, and by inhalation.
  • The drug is sold in the form of prolonged and rapid release. Prolonged forms are taken in the morning or in the afternoon.
  • The drug is prohibited for use by anti-doping rules.
  • Adderall acts by increasing the activity of the dopamine and norepinephrine neurotransmitters in the person’s brain. Adderall duplicates numerous chemical and pharmacological reactions of endogenous neurotransmitters, especially phenethylamine and methylphenethylamine, and this last isomer of amphetamine is produced in the human body.
  • Increased dosages disrupt the work of short-term memory and cognitive processes.
  • Adderall increases endurance and reaction time, primarily, by inhibiting the dopamine re-uptake.
  • This drug is well tolerated and effective, especially in terms of treatment of neuroleptic and ADHD. But taking Adderall for a long time, there can be a number of side effects. In particular:
  • tachycardia;
  • excessive euphoria;
  • increased anxiety.
  • Studies using a magnetic resonance imaging show that a prolonged treatment with the drug leads to a decrease in the anomalies in the structure of the brain and functions in patients with ADHD, improves the work of some parts of the brain such as the caudate nucleus in the basal ganglia.
  • Adderall has some contraindications. It cannot be used if a person has:
  • glaucoma
  • arterial hypertension and cardiovascular pathologies
  • drug addiction
  • hyperthyroidism
  • atherosclerosis
  • heart disease
  • neurotic disorders
  • mental disorders and diseases of the nervous system, and
  • kidney and liver failure
  • Doctors prescribe Adderall with special care if a person suffers from depressions and bipolar disorder. As well, Adderall should not be taken in the case of epilepsy, the Rhine syndrome, and acute psychosis.
  • When taking Adderall, the following symptoms may be observed: dry mouth, difficulty swallowing, palpitations, dyspeptic disorders, sexual dysfunction (problems with libido and erection in men). Also, there can be vegetative disorders, superficial sleep, aggressiveness, and obsessive-compulsive disorders.
  • The withdrawal syndrome may occur if the drug is discontinued abruptly. Symptoms of withdrawal are anxiety, depressed mood, fatigue, increased appetite, lack of motivation, insomnia or drowsiness.
  • Large doses of the drug worsen cognitive functions and cause rapid muscle destruction.
  • Drug dependence is a serious risk of abuse of Adderall; however, it rarely occurs with therapeutic use. Very high doses can lead to a psychotic state (for example, delirium and paranoia), which is rarely met with a therapeutic dosage even with prolonged use.
  • Allergic reactions such as skin redness may occur when taking Adderall. Therefore, before you start taking Adderall, you must tell your doctor about any unusual symptoms that you noticed.